proposed SPAN neurological scoring system

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Some deficits in our scoring system are not present at the late phase.  To make scoring the stroke animals easy, I proposed modifying it and naming it the SPAN neurological scoring system (28 points).

The details to score the stroke animals

General Status (0-6)

The animal is placed in a new cage with bedding and watched for 5 minutes.

Spontaneous activity (0-2)

0 point: Brisk, can stand up by holding walls; 1 point: Walks but can’t stand up by holding walls; and 2 points: Trends to rest

 Body symmetry (0-2)

0 point: Posture shift to both sides; 1 point: Posture shifts to one side continuously; and 2 points: Posture shifts to one side, but hardly walks

The animal is placed on the table surface and watched.

Gait (0-2)

0 point: Walk freely, no abnormality; 1 point: Supports left extremities by right; and 2 points: Clear limping or body swinging

Motor Functions (0-12)

The animal is on the table. The tail is held up, and the front legs are allowed to touch the table surface.

 Front limb symmetry (0-2)

0 point: Stretches both arms symmetrically; 1 point: Asymmetry, difference less than 45 degrees; and 2 points: Asymmetry, difference more than 45 degrees

 The animal is placed on the table and allowed to walk freely.

Circling / bench top (0-2)

0 point: Turns to both sides equally; 1 point: Tendency to turn to one side, can walk straight; and 2 points: Circles to one side

The animal is on the table. The tail is held up, and only the front limbs are allowed to walk on the table surface.

Circling / holding tail (0-2)

0 point: Walks in both directions; 1 point: Tendency to circle to one side, occasionally turns to the other side; and 2 points: Circles to one side

The animal is on the table. The hind limbs are left outside the table.

Hind limb placement (0-2)

0 point: Immediately place on the table; 1 point: Slowly place on the table; and 2 points: Fail to place on the table

The animal is placed on the screen, which is then turned almost vertically.

Screen climb (0-2)

0 point: Completes climbing, shifts to both sides; 1 point: Climbs and shifts to one side; and 2 points: Does not climb

The animal is placed in the middle of the beam and allowed to walk.

Beam walking (0-2)

0 point: Reaches up to the end wall; 1 point: Can walk on the beam but does not reach up to the end wall; and 2 points: Can’t walk on the beam

Sensory functions (0-10)

The animal is placed on the table and allowed to move freely. Use the needle to touch when the animal is not walking.

Front limb touch (0-2)

0 point: Brisk on both sides; 1 point: Slow left and brisk right; and 2 points: Absent left and some responses right

Hind limb touch (0-2)

0 point: Brisk on both sides; 1 point: Slow left and brisk right; and 2 points: Absent left and some responses right

Animal is placed inside the cage. Use the needle to touch the truck, vibrissae, and face.

Trunk touch (0-2)

0 point: Brisk bilaterally; 1 point: Slow left and brisk right; and 2 points: Absent left and some responses right

 Vibrissae touch (0-2)

0 point: Brisk bilaterally; 1 point: Slow left and brisk right; and 2 points: Absent left and some responses right

Face touch (0-2)

0 point: Brisk on both sides; 1 point: Slow left and brisk right; and 2 points: Absent left and some responses rightSPAN